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Effect of bicarbonate on iron-mediated oxidation of low-density lipoprotein

Oxidation of low-density lipoprotein (LDL) may play an important role in atherosclerosis. We studied the effects of bicarbonate/CO(2) and phosphate buffer systems on metal ion-catalyzed oxidation of LDL to malondialdehyde (MDA) and to protein carbonyl and MetO derivatives. Our results revealed that...

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Autori principali: Arai, Hirofumi, Berlett, Barbara S., Chock, P. Boon, Stadtman, Earl R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176232/
https://ncbi.nlm.nih.gov/pubmed/16027354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504685102
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