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Oxidized messenger RNA induces translation errors

To investigate the effect of RNA oxidation on normal cellular functions, we studied the translation of nonoxidized and oxidized luciferase mRNA in both rabbit reticulocyte lysate and human HEK293 cells. When HEK293 cells transfected with nonoxidized mRNA encoding the firefly luciferase protein were...

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Detalhes bibliográficos
Main Authors: Tanaka, Mikiei, Chock, P. Boon, Stadtman, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765478/
https://ncbi.nlm.nih.gov/pubmed/17190801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609737104
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