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Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice
Direct communication between arteries and veins without intervening capillary beds is the primary pathology of arteriovenous malformations (AVMs). Although Notch signaling is implicated in embryonic arteriovenous (AV) differentiation, its function in the adult mammalian vasculature has not been esta...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1175015/ https://ncbi.nlm.nih.gov/pubmed/15994223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504391102 |
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