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The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of β-like globin genes

To investigate the function of transcription factor Sp1 in β-like globin gene activation, we analyzed the recruitment of Sp1, fetal Krüppel-like factor 2 (FKLF2), and related factors at the human β-globin locus in a human fetal liver and mouse erythroleukemia hybrid cell (A181γ cell) that contains a...

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Bibliografiske detaljer
Main Authors: Feng, Dongxiao, Kan, Yuet Wai
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174987/
https://ncbi.nlm.nih.gov/pubmed/15998736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502041102
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