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5′HS5 of the Human β-globin Locus Control Region Is Dispensable for the Formation of the β-globin Active Chromatin Hub

Hypersensitive site 5 (5′HS5) of the β-globin Locus Control Region functions as a developmental stage-specific border in erythroid cells. Here, we have analyzed the role of 5′HS5 in the three dimensional organization of the β-gene locus using the Chromatin Conformation Capture (3C) technique. The re...

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Detalhes bibliográficos
Main Authors: Chan, Ping Kei, Wai, Albert, Philipsen, Sjaak, Tan-Un, Kian-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2358975/
https://ncbi.nlm.nih.gov/pubmed/18461170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002134
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