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Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

Amyotrophic lateral sclerosis is a neurodegenerative syndrome associated with 114 mutations in the gene encoding the cytosolic homodimeric enzyme Cu/Zn superoxide dismutase (SOD). In this article, we report that amyotrophic lateral sclerosis-associated SOD mutations with distinctly different disease...

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Detalhes bibliográficos
Main Authors: Lindberg, Mikael J., Byström, Roberth, Boknäs, Niklas, Andersen, Peter M., Oliveberg, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174986/
https://ncbi.nlm.nih.gov/pubmed/15987780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501957102
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