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Protein folding mediated by solvation: Water expulsion and formation of the hydrophobic core occur after the structural collapse

The interplay between structure-search of the native structure and desolvation in protein folding has been explored using a minimalist model. These results support a folding mechanism where most of the structural formation of the protein is achieved before water is expelled from the hydrophobic core...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Cheung, Margaret S., García, Angel E., Onuchic, José N.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022387699
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