Protein folding mediated by solvation: Water expulsion and formation of the hydrophobic core occur after the structural collapse
The interplay between structure-search of the native structure and desolvation in protein folding has been explored using a minimalist model. These results support a folding mechanism where most of the structural formation of the protein is achieved before water is expelled from the hydrophobic core...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805324/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022387699 |
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