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Protein folding mediated by solvation: Water expulsion and formation of the hydrophobic core occur after the structural collapse
The interplay between structure-search of the native structure and desolvation in protein folding has been explored using a minimalist model. These results support a folding mechanism where most of the structural formation of the protein is achieved before water is expelled from the hydrophobic core...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117366/ https://ncbi.nlm.nih.gov/pubmed/11805324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022387699 |
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