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Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides
Classical ligands bind to the extracellular surface of their cognate receptors and activate signaling pathways without crossing the plasma membrane barrier. We selectively targeted the intracellular receptor–G protein interface by using cell-penetrating membrane-tethered peptides. Attachment of a pa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117359/ https://ncbi.nlm.nih.gov/pubmed/11805322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022460899 |
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