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Structural Determinants of Ras-Raf Interaction Analyzed in Live Cells

The minimum structure of the Raf-1 serine/threonine kinase that recognizes active Ras was used to create a green fluorescent fusion protein (GFP) for monitoring Ras activation in live cells. In spite of its ability to bind activated Ras in vitro, the Ras binding domain (RBD) of Raf-1 (Raf-1[51-131]G...

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Detalhes bibliográficos
Main Authors: Bondeva, Tzvetanka, Balla, András, Várnai, Péter, Balla, Tamas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117316/
https://ncbi.nlm.nih.gov/pubmed/12134072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-01-0019
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