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Suppression of Integrin Activation by Activated Ras or Raf Does Not Correlate with Bulk Activation of ERK MAP Kinase

The rapid modulation of ligand-binding affinity (“activation”) is a central property of the integrin family of cell adhesion receptors. The Ras family of small GTP-binding proteins and their downstream effectors are key players in regulating integrin activation. H-Ras can suppress integrin activatio...

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Autori principali: Hughes, Paul E., Oertli, Beat, Hansen, Malene, Chou, Fan-Li, Willumsen, Berthe M., Ginsberg, Mark H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC117310/
https://ncbi.nlm.nih.gov/pubmed/12134066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-10-0480
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