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Design of a novel triple helix-forming oligodeoxyribonucleotide directed to the major promoter of the c-myc gene

Altered expression of c-myc is implicated in pathogenesis and progression of many human cancers. Triple helix-forming oligonucleotides (TFOs) directed to a polypurine/polypyrimidine sequence in a critical regulatory region near the c-myc P2 promoter have been shown to inhibit c-myc transcription in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: McGuffie, E. M., Catapano, C. V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12060688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf376
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