Design of a novel triple helix-forming oligodeoxyribonucleotide directed to the major promoter of the c-myc gene
Altered expression of c-myc is implicated in pathogenesis and progression of many human cancers. Triple helix-forming oligonucleotides (TFOs) directed to a polypurine/polypyrimidine sequence in a critical regulatory region near the c-myc P2 promoter have been shown to inhibit c-myc transcription in...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12060688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf376 |
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