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Effects of macromolecular crowding on protein folding and aggregation.

We have studied the effects of polysaccharide and protein crowding agents on the refolding of oxidized and reduced hen lysozyme in order to test the prediction that association constants of interacting macromolecules in living cells are greatly increased by macromolecular crowding relative to their...

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Autori principali: van den Berg, B, Ellis, R J, Dobson, C M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171756/
https://ncbi.nlm.nih.gov/pubmed/10601015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.24.6927
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