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Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell

We have studied the effects of macromolecular crowding on protein folding kinetics by studying the oxidative refolding of hen lysozyme in the absence and presence of high concentrations of bovine serum albumin and Ficoll 70. The heterogeneity characteristic of the lysozyme refolding process is prese...

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Autors principals: van den Berg, Bert, Wain, Rachel, Dobson, Christopher M., Ellis, R.John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC306593/
https://ncbi.nlm.nih.gov/pubmed/10921869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.3870
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