p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons.

Activation of cytosolic phospholipase A(2 )(cPLA(2)) is a prerequisite for the formation of the transcription factor complex interferon-stimulated gene factor 3 (ISGF3) in response to interferon-alpha (IFN-alpha). Here we show that p38 mitogen-activated protein kinase (MAPK), an activator of cPLA(2)...

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Hlavní autoři: Goh, K C, Haque, S J, Williams, B R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171628/
https://ncbi.nlm.nih.gov/pubmed/10523304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5601
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