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p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons.
Activation of cytosolic phospholipase A(2 )(cPLA(2)) is a prerequisite for the formation of the transcription factor complex interferon-stimulated gene factor 3 (ISGF3) in response to interferon-alpha (IFN-alpha). Here we show that p38 mitogen-activated protein kinase (MAPK), an activator of cPLA(2)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171628/ https://ncbi.nlm.nih.gov/pubmed/10523304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5601 |
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