Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.

समान संसाधन

• Twenty proteins containing a C-terminal SOCS box form five structural classes
  द्वारा: Hilton, Douglas J., और अन्य
  प्रकाशित: (1998)
• Cutting Edge: SOCS-1 Is a Potent Inhibitor of IL-4 Signal Transduction()
  द्वारा: Losman, J. A., और अन्य
  प्रकाशित: (1999)
• The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
  द्वारा: Zhang, Jian-Guo, और अन्य
  प्रकाशित: (2001)
• Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.
  द्वारा: Hilton, D J, और अन्य
  प्रकाशित: (1994)
• SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation
  द्वारा: Krebs, Danielle L., और अन्य
  प्रकाशित: (2002)