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Cutting Edge: SOCS-1 Is a Potent Inhibitor of IL-4 Signal Transduction()

IL-4 is an important regulator of the activation, proliferation, and differentiation of many hematopoetic cells. Many of these biological effects result from the activation of Janus kinases (JAK)1 and JAK3 and the transcription factor Stat6. Recent data suggest that members of the SOCS (suppressor o...

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Detalhes bibliográficos
Main Authors: Losman, J. A., Chen, X. P., Hilton, D., Rothman, P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836448/
https://ncbi.nlm.nih.gov/pubmed/10201892
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