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The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.

Most cases of autosomal dominant polycystic kidney disease (ADPKD) are the result of mutations in the PKD1 gene. The PKD1 gene codes for a large cell-surface glycoprotein, polycystin-1, of unknown function, which, based on its predicted domain structure, may be involved in protein-protein and protei...

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Bibliografiske detaljer
Main Authors: Bycroft, M, Bateman, A, Clarke, J, Hamill, S J, Sandford, R, Thomas, R L, Chothia, C
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171124/
https://ncbi.nlm.nih.gov/pubmed/9889186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.2.297
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