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The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.
Most cases of autosomal dominant polycystic kidney disease (ADPKD) are the result of mutations in the PKD1 gene. The PKD1 gene codes for a large cell-surface glycoprotein, polycystin-1, of unknown function, which, based on its predicted domain structure, may be involved in protein-protein and protei...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171124/ https://ncbi.nlm.nih.gov/pubmed/9889186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.2.297 |
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