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Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system.
The functional coupling of protein synthesis and chaperone-assisted folding in vivo has remained largely unexplored. Here we have analysed the chaperonin-dependent folding pathway of actin in yeast. Remarkably, overexpression of a heterologous chaperonin which traps non-native polypeptides does not...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171104/ https://ncbi.nlm.nih.gov/pubmed/9878052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.1.75 |
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