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Essential role of the chaperonin folding compartment in vivo

The GroEL/GroES chaperonin system of Escherichia coli forms a nano-cage allowing single protein molecules to fold in isolation. However, as the chaperonin can also mediate folding independently of substrate encapsulation, it remained unclear whether the folding cage is essential in vivo. To address...

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Bibliografske podrobnosti
Main Authors: Tang, Yun-Chi, Chang, Hung-Chun, Chakraborty, Kausik, Hartl, F Ulrich, Hayer-Hartl, Manajit
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396394/
https://ncbi.nlm.nih.gov/pubmed/18418386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.77
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