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Essential role of the chaperonin folding compartment in vivo

The GroEL/GroES chaperonin system of Escherichia coli forms a nano-cage allowing single protein molecules to fold in isolation. However, as the chaperonin can also mediate folding independently of substrate encapsulation, it remained unclear whether the folding cage is essential in vivo. To address...

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Detalhes bibliográficos
Main Authors: Tang, Yun-Chi, Chang, Hung-Chun, Chakraborty, Kausik, Hartl, F Ulrich, Hayer-Hartl, Manajit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396394/
https://ncbi.nlm.nih.gov/pubmed/18418386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.77
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