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Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.
To investigate the role of the src homology 2 (SH2)-containing inositol 5' phosphatase (SHIP) in growth factor-mediated signalling, we compared Steel factor (SF)-induced events in bone marrow-derived mast cells (BMMCs) from SHIP-/- and SHIP+/+ littermates. We found SF alone stimulated massive d...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1998
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171077/ https://ncbi.nlm.nih.gov/pubmed/9857188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7311 |
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