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Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress.

To study the role of protein kinase B (PKB) in response to cellular stress, we examined PKBalpha activity following different stress treatments. Hyperosmotic but not chemical stress resulted in inactivation of PKBalpha and prevented activation by pervanadate and mitogens. Hyperosmotic shock did not...

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Detalhes bibliográficos
Main Authors: Meier, R, Thelen, M, Hemmings, B A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171075/
https://ncbi.nlm.nih.gov/pubmed/9857186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7294
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