Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is an essential physiological process in development, yet also plays a major role in the progression of human diseases such as diabetic retinopathy, atherosclerosis and cancer. The effects of the most potent angiogenic factors,...

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Bibliographic Details
Main Authors: Mohammadi, M, Froum, S, Hamby, J M, Schroeder, M C, Panek, R L, Lu, G H, Eliseenkova, A V, Green, D, Schlessinger, J, Hubbard, S R
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170917/
https://ncbi.nlm.nih.gov/pubmed/9774334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.20.5896
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