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Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.
Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is an essential physiological process in development, yet also plays a major role in the progression of human diseases such as diabetic retinopathy, atherosclerosis and cancer. The effects of the most potent angiogenic factors,...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170917/ https://ncbi.nlm.nih.gov/pubmed/9774334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.20.5896 |
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