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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

Receptor tyrosine kinases Flt-1 and Flk-1/KDR, and their ligand, the vascular endothelial growth factor (VEGF), were shown to be essential for angiogenesis in the mouse embryo by gene targeting. Flk-1/KDR null mutant mice exhibited impaired endothelial and hematopoietic cell development. On the othe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hiratsuka, Sachie, Minowa, Osamu, Kuno, Junko, Noda, Tetsuo, Shibuya, Masabumi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 1998
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC21341/
https://ncbi.nlm.nih.gov/pubmed/9689083
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