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Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint.

M-phase-promoting factor (MPF), a complex of cdc2 and a B-type cyclin, is a key regulator of the G2/M cell cycle transition. Cyclin B1 accumulates in the cytoplasm through S and G2 phases and translocates to the nucleus during prophase. We show here that cytoplasmic localization of cyclin B1 during...

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Bibliografiske detaljer
Main Authors: Toyoshima, F, Moriguchi, T, Wada, A, Fukuda, M, Nishida, E
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170613/
https://ncbi.nlm.nih.gov/pubmed/9582266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.10.2728
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