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Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal

Smad family proteins play a pivotal role in transmitting the transforming growth factor-β (TGF-β) superfamily signals from the cell surface to the nucleus. In response to ligand stimulation, Smad4 forms a complex with respective receptor-specific Smads, and the complex translocates into the nucleus...

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Detalhes bibliográficos
Main Authors: Watanabe, Mina, Masuyama, Norihisa, Fukuda, Makoto, Nishida, Eisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084261/
https://ncbi.nlm.nih.gov/pubmed/11265759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd029
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