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Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint.
M-phase-promoting factor (MPF), a complex of cdc2 and a B-type cyclin, is a key regulator of the G2/M cell cycle transition. Cyclin B1 accumulates in the cytoplasm through S and G2 phases and translocates to the nucleus during prophase. We show here that cytoplasmic localization of cyclin B1 during...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170613/ https://ncbi.nlm.nih.gov/pubmed/9582266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.10.2728 |
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