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Turning off the G2 DNA damage checkpoint

In response to DNA damage, cells activate checkpoints to delay cell cycle progression and allow time for completion of DNA repair before commitment to S-phase or mitosis. During G2, many proteins collaborate to activate Chk1, an effector protein kinase that ensures the mitotic cyclin-dependent kinas...

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Detalles Bibliográficos
Main Authors: Calonge, Teresa M., O'Connell, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233850/
https://ncbi.nlm.nih.gov/pubmed/17851138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.07.017
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