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A predictive mathematical model of the DNA damage G2 checkpoint

A predictive mathematical model of the transition from the G2 phase in the cell cycle to mitosis (M) was constructed from the known interactions of the proteins that are thought to play significant roles in the G2 to M transition as well as the DNA damage- induced G2 checkpoint. The model simulates...

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Autors principals: Kesseler, Kevin J., Blinov, Michael L., Elston, Timothy C., Kaufmann, William K., Simpson, Dennis A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654547/
https://ncbi.nlm.nih.gov/pubmed/23266715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.12.011
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