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A predictive mathematical model of the DNA damage G2 checkpoint

A predictive mathematical model of the transition from the G2 phase in the cell cycle to mitosis (M) was constructed from the known interactions of the proteins that are thought to play significant roles in the G2 to M transition as well as the DNA damage- induced G2 checkpoint. The model simulates...

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Détails bibliographiques
Auteurs principaux: Kesseler, Kevin J., Blinov, Michael L., Elston, Timothy C., Kaufmann, William K., Simpson, Dennis A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654547/
https://ncbi.nlm.nih.gov/pubmed/23266715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.12.011
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