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CFTR Cl- channel and CFTR-associated ATP channel: distinct pores regulated by common gates.

The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that is regulated by phosphorylation of the R domain and ATP hydrolysis at two nucleotide-binding domains (NBDs). It is controversial whether CFTR conducts ATP or whether CFTR might be closely associated with a sepa...

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Detalhes bibliográficos
Main Authors: Sugita, M, Yue, Y, Foskett, J K
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170439/
https://ncbi.nlm.nih.gov/pubmed/9463368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.898
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