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On the Mechanism of MgATP-dependent Gating of CFTR Cl(−) Channels

CFTR, the product of the gene mutated in cystic fibrosis, is an ATPase that functions as a Cl(−) channel in which bursts of openings separate relatively long interburst closed times (τib). Channel gating is controlled by phosphorylation and MgATP, but the underlying molecular mechanisms remain contr...

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Bibliografski detalji
Glavni autori: Vergani, Paola, Nairn, Angus C., Gadsby, David C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217317/
https://ncbi.nlm.nih.gov/pubmed/12508051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028673
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