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Determinants of protein-protein recognition by four helix bundles: changing the dimerization specificity of Tet repressor.

Homo- and heterodimerization is essential for the activity of many proteins, particularly transcription factors. One widely distributed structural motif for protein recognition is the four helix bundle. To understand the molecular details determining specificity of subunit recognition in a dimer for...

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Detalhes bibliográficos
Principais autores: Schnappinger, D, Schubert, P, Pfleiderer, K, Hillen, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170403/
https://ncbi.nlm.nih.gov/pubmed/9430644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.2.535
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