Amino acids determining operator binding specificity in the helix-turn-helix motif of Tn10 Tet repressor.

Each of 22 amino acids in the proposed alpha-helix-turn-alpha-helix operator binding motif of the Tn10 encoded Tet repressor was replaced by alanine and one residue was replaced by valine to determine their role in tet operator recognition by a 'loss of contact' analysis with 16 operator v...

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Bibliographic Details
Main Authors: Wissmann, A, Baumeister, R, Müller, G, Hecht, B, Helbl, V, Pfleiderer, K, Hillen, W
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC453165/
https://ncbi.nlm.nih.gov/pubmed/1756721
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