Amino acids determining operator binding specificity in the helix-turn-helix motif of Tn10 Tet repressor.

Each of 22 amino acids in the proposed alpha-helix-turn-alpha-helix operator binding motif of the Tn10 encoded Tet repressor was replaced by alanine and one residue was replaced by valine to determine their role in tet operator recognition by a 'loss of contact' analysis with 16 operator variants. O...

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Bibliografske podrobnosti

izdano v:	EMBO J
Principais autores:	Wissmann, A, Baumeister, R, Müller, G, Hecht, B, Helbl, V, Pfleiderer, K, Hillen, W
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 1991
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1756721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04992.x
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