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Control of B cell development by Ras-mediated activation of Raf.

Cell fate commitment in a variety of lineages requires signals conveyed via p21ras. To examine the role of p21ras in the development of B lymphocytes, we generated transgenic mice expressing a dominant-negative form of Ras in B lymphocyte progenitors, using a novel transcriptional element consisting...

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Autors principals: Iritani, B M, Forbush, K A, Farrar, M A, Perlmutter, R M
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170305/
https://ncbi.nlm.nih.gov/pubmed/9384581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.23.7019
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