Complementation of null CF mice with a human CFTR YAC transgene.

We have made transgenic mice carrying a 320 kb YAC with the intact human cystic fibrosis transmembrane regulator (CFTR) gene. Mice that only express the human transgene were obtained by breeding with Cambridge null CF mice. One line has approximately two copies of the intact YAC. Mice carrying this...

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Main Authors: Manson, A L, Trezise, A E, MacVinish, L J, Kasschau, K D, Birchall, N, Episkopou, V, Vassaux, G, Evans, M J, Colledge, W H, Cuthbert, A W, Huxley, C
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170049/
https://ncbi.nlm.nih.gov/pubmed/9250667
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