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Stimulation of V(D)J cleavage by high mobility group proteins.
V(D)J recombination requires a pair of signal sequences with spacer lengths of 12 and 23 bp between the conserved heptamer and nonamer elements. The RAG1 and RAG2 proteins initiate the reaction by making double-strand DNA breaks at both signals, and must thus be able to operate on these two differen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169877/ https://ncbi.nlm.nih.gov/pubmed/9184213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.10.2665 |
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