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Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation.
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells and keratinocytes. It is demonstrated that HB-EGF is not only a ligand for HER1, as previously reported, but for HER4 as well. HB-EGF binds to NIH 3T3 c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169725/ https://ncbi.nlm.nih.gov/pubmed/9135143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1268 |
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