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Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation.

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells and keratinocytes. It is demonstrated that HB-EGF is not only a ligand for HER1, as previously reported, but for HER4 as well. HB-EGF binds to NIH 3T3 c...

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Autors principals: Elenius, K, Paul, S, Allison, G, Sun, J, Klagsbrun, M
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169725/
https://ncbi.nlm.nih.gov/pubmed/9135143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1268
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