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N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration

Heparin-binding epidermal growth factor-like growth factor (HB-EGF), a mitogen and chemotactic factor, binds to two receptor tyrosine kinases, erbB1 and erbB4. Now we demonstrate that HB-EGF also binds to a novel 140 kDa receptor on MDA-MB 453 cells. Purification of this receptor showed it to be ide...

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Detalhes bibliográficos
Main Authors: Nishi, Eiichiro, Prat, Annik, Hospital, Véronique, Elenius, Klaus, Klagsbrun, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125525/
https://ncbi.nlm.nih.gov/pubmed/11432822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3342
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