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Role of SHPS-1 in the Regulation of Insulin-like Growth Factor I–stimulated Shc and Mitogen-activated Protein Kinase Activation in Vascular Smooth Muscle Cells

Insulin-like growth factor I (IGF-I) stimulates smooth muscle cell (SMC) proliferation, and the mitogen-activated protein kinase (MAPK) pathway plays an important role in mediating IGF-I–induced mitogenic signaling. Our prior studies have shown that recruitment of Src homology 2 domain tyrosine phos...

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Autori principali: Ling, Yan, Maile, Laura A., Lieskovska, Jaroslava, Badley-Clarke, Jane, Clemmons, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165417/
https://ncbi.nlm.nih.gov/pubmed/15888547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0918
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