Sensitivity of Human Immunodeficiency Virus Type 1 to the Fusion Inhibitor T-20 Is Modulated by Coreceptor Specificity Defined by the V3 Loop of gp120

T-20 is a synthetic peptide that potently inhibits replication of human immunodeficiency virus type 1 by interfering with the transition of the transmembrane protein, gp41, to a fusion active state following interactions of the surface glycoprotein, gp120, with CD4 and coreceptor molecules displayed...

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Publicat a:	J Virol
Autors principals:	Derdeyn, Cynthia A., Decker, Julie M., Sfakianos, Jeffrey N., Wu, Xiaoyun, O'Brien, William A., Ratner, Lee, Kappes, John C., Shaw, George M., Hunter, Eric
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2000
Matèries:	Vaccines and Antiviral Agents
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.18.8358-8367.2000
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