Defective calcium handling and insulin release in islets from diabetic Chinese hamsters.

In pancreatic islets from normal Chinese hamsters preloaded with 45Ca2+, glucose-induced biphasic insulin release was associated with increased 45Ca2+ efflux; islets from diabetic hamsters showed decreased insulin release and no increase in 45Ca2+ efflux. The lack of stimulated 45Ca2+ efflux persist...

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Bibliografiske detaljer
Main Authors: Siegel, E G, Wollheim, C B, Sharp, G W, Herberg, L, Renold, A E
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1161038/
https://ncbi.nlm.nih.gov/pubmed/384998
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