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Transcription-Dependent Nuclear-Cytoplasmic Trafficking Is Required for the Function of the von Hippel-Lindau Tumor Suppressor Protein

Mutation of the von Hippel-Lindau tumor suppressor gene (vhl) causes the von Hippel-Lindau cancer syndrome as well as sporadic renal clear cell carcinoma. To pursue our study of the intracellular localization of VHL protein in relation to its function, we fused VHL to the green fluorescent protein (...

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Publicat a:Mol Cell Biol
Autors principals: Lee, Stephen, Neumann, Markus, Stearman, Robert, Stauber, Roland, Pause, Arnim, Pavlakis, George N., Klausner, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1999
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9891082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.2.1486
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