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Retinoblastoma Protein Contains a C-terminal Motif That Targets It for Phosphorylation by Cyclin-cdk Complexes

Stable association of certain proteins, such as E2F1 and p21, with cyclin-cdk2 complexes is dependent upon a conserved cyclin-cdk2 binding motif that contains the core sequence ZRXL, where Z and X are usually basic. In vitro phosphorylation of the retinoblastoma tumor suppressor protein, pRB, by cyc...

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Detalhes bibliográficos
Main Authors: Adams, Peter D., Li, Xiaotong, Sellers, William R., Baker, Kayla B., Leng, Xiaohong, Harper, J. Wade, Taya, Yoichi, Kaelin, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116037/
https://ncbi.nlm.nih.gov/pubmed/9891042
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