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Replicating Adenoviruses That Target Tumors with Constitutive Activation of the wnt Signaling Pathway

Despite important advances in understanding the molecular basis of cancer, few treatments have been devised which rationally target known causal oncogenic defects. Selectively replicating viruses have a major advantage over nonreplicating viruses to target these defects because the therapeutic effec...

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Autori principali: Brunori, Michele, Malerba, Maddalena, Kashiwazaki, Haruhiko, Iggo, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC115912/
https://ncbi.nlm.nih.gov/pubmed/11222711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2857-2865.2001
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